Anna  E  Czapar

Entering Class: 2012
PhD Program: Pathology
Advisor: Nicole Steinmetz, PhD

Undergraduate Institution: University of Illinois
Hometown: Rochester, IL.

Research Interests: Targeted delivery of therapeutics using viral nanoparticles.

About me: Outside of lab I like riding my bike, running, cross-country skiing, baking, reading, and drinking too much coffee.

Comment about the MSTP program: The MSTP at Case is full of brilliant, helpful, and dedicated students and faculty. I feel lucky to be a part of it.

Featured Publication:

Czapar AE, Steinmetz NF. Plant viruses and bacteriophages for drug delivery in medicine and biotechnology. Curr Opin Chem Biol. 2017 Jun;38:108-116. doi: 10.1016/j.cbpa.2017.03.013. Epub 2017 Apr 17. Review. PubMed PMID: 28426952; PubMed Central PMCID: PMC5488792.

Additional Publications:

Bludau H*, Czapar AE*, Pitek AS, Shukla S, Jordan R, Steinmetz NF. POxylation as an alternative stealth coating for biomedical applications. Eur Polym J. 2017 Mar;88:679-688. doi: 10.1016/j.eurpolymj.2016.10.041. Epub 2016 Nov 5. PubMed PMID: 28713172; PubMed Central PMCID: PMC5510027. *Co-first authors

Shukla S, Myers JT, Woods SE, Gong X, Czapar AE, Commandeur U, Huang AY, Levine AD, Steinmetz NF. Plant viral nanoparticles-based HER2 vaccine: Immune response influenced by differential transport, localization and cellular interactions of particulate carriers. Biomaterials. 2017 Mar;121:15-27. doi: 10.1016/j.biomaterials.2016.12.030. Epub 2016 Dec 27. PubMed PMID: 28063980.

Wallat JD, Czapar AE, Wang C, Wen AM, Wek KS, Yu X, Steinmetz NF, Pokorski JK. Optical and Magnetic Resonance Imaging Using Fluorous Colloidal Nanoparticles. Biomacromolecules. 2017 Jan 9;18(1):103-112. doi: 10.1021/acs.biomac.6b01389. Epub 2016 Dec 19. PubMed PMID: 27992176.

Czapar AE, Zheng YR, Riddell IA, Shukla S, Awuah SG, Lippard SJ, Steinmetz NF. Tobacco Mosaic Virus Delivery of Phenanthriplatin for Cancer therapy. ACS Nano. 2016 Apr 26;10(4):4119-26. doi: 10.1021/acsnano.5b07360. Epub 2016 Mar 28. PubMed PMID: 26982250; PubMed Central PMCID: PMC5155116.

Bruckman MA, Czapar AE, VanMeter A, Randolph LN, Steinmetz NF. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. J Control Release. 2016 Jun 10;231:103-13. doi: 10.1016/j.jconrel.2016.02.045. Epub 2016 Mar 3. PubMed PMID: 26941034; PubMed Central PMCID: PMC5207211.

Wen, A.M., M. Infusino, A. De Luca, D.L. Kernan, A.E. Czapar, G. Strangi, and N.F. Steinmetz, Interface of physics and biology: engineering virus-based nanoparticles for biophotonics. Bioconjug Chem, 2015. 26(1): p. 51-62. PMID: 25541212 [PubMed - in process] PMCID: PMC4306514

Czapar, A.E. and Steinmetz, N.F., Paving the Way Toward Translational Application of Virus-Based Nanoparticles (VNPs): Preclinical Evaluation of Their Biological Fates, In: Nanomaterials in Pharmacology, Z.R.Lu ed., Springer Press, In press

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