Tim  Y.  Mariano

Entering Class: 2003
PhD Program: Biomedical Engineering
Advisor: Ken Gustafson
Laboratory: Neural Engineering Center

Undergraduate Institution: Harvard University
Hometown: Natick, MA.

Research Interests: Neuroprostheses for restoration of bladder and motor function after spinal cord injury, role of orbital prefrontal cortex in cognitive deficits associated with neurodegenerative diseases such as Alzheimer's.

About me:

S.B., Harvard University, 2003

M.Sc., University of Oxford, 2006

Ph.D., Case Western Reserve University, 2009

Neurotree entry.

Epernicus entry.

Comment about the MSTP program:

Featured Publication:

Mariano TY*, Bannerman DM*, McHugh SB, Preston TJ, Rudebeck PH, Rudebeck SR, Rawlins JNP, Walton ME, Rushworth MFS, Baxter MG, Campbell TG. Impulsive choice in hippocampal but not orbitofrontal cortex-lesioned rats on a non-spatial decision-making maze task. Eur. J. Neurosci. 2009 Aug; 30(3):472-484, doi:10.1111/j.1460-9568.2009.06837.x. Published online 2009 Jul. 28. PubMed abstract.
* joint first authors

Additional Publications:

Mariano TY, Bhadra N, Gustafson KJ. Suppression of reflex urethral responses by sacral dermatome stimulation in an acute spinalized feline model. Neurourol. Urodyn. Published online 2009 Mar. 12, doi: 10.1002/nau.20717. PubMed abstract.

Bhadra N, Gustafson KJ, Bruns TM, Mariano TY. System and method for bladder and sphincter control. United States patent application 12417529. 2009.

Mariano TY, Boger AS, Gustafson KJ. The feline dorsal nerve of the penis arises from the deep perineal nerve and not the sensory afferent branch. Anat. Histol. Embryol. 2008 Jun; 37(3):166-168, doi: 10.1111/j.1439-0264.2007.00815.x. Published online 2007 Oct. 5. PubMed abstract.

Mariano TY, Bhadra N, Gustafson KJ. Suppression of urethral reflex contractions in an acute spinal feline model. Society for Neuroscience Annual Meeting. 2008.

Mariano TY, Bhadra N, Gustafson KJ. Afferent stimulation reduces urethral sphincter reflexes. Biomedical Engineering Society Annual Fall Meeting. 2008.

Mariano TY, Bhadra N, Gustafson KJ. Quantification and suppression of reflex urethral contractions in the acute spinal feline. Neural Interfaces Conference. 2008.

Mariano TY, Bhadra N, Boger AS, Gustafson KJ. Characterizing reflex external urethral sphincter activity in the acute spinalized feline. Society for Neuroscience Annual Meeting. 2007.

Mariano TY, McHugh SB, Rudebeck P, Baxter MG, Bannerman DM. Dissociations of function between the rodent orbital frontal cortex and hippocampus. FENS Abstr, vol. 3, A089.18. 2006.

Gustafson KJ, Bhadra N, Bhadra N, Kilgore KL, Boger AS, Parks J, Mariano T. Reversible High Frequency Alternating Current Block of the Feline Pudendal Nerve. Biomedical Engineering Society Annual Fall Meeting. 2005.

Bhadra N, Mariano T, Bhadra N, Kilgore K, Creasey GH, Rackley R, Vasavada S, Gustafson KJ. Reversible high frequency deep perineal nerve block for the potential treatment of sphincter dyssynergia. American Urological Association Meeting. 2005.

Talks:

Mariano TY. "Suppression of Reflex Urethral Responses by Sacral Dermatome Stimulation in an Acute Spinalized Feline Model." Medical Scientist Training Program Winter Retreat, Case Western Reserve University, Cleveland, OH. 2009 February 12.

Mariano TY. "Suppression of Reflex Urethral Responses by Surface Stimulation in the Acute Spinal Feline." Functional Electrical Stimulation Center Seminar, MetroHealth Medical Center, Cleveland, OH. 2008 December 17.

Mariano TY. "Suppression of Reflex Urethral Responses by Afferent Stimulation in an Acute Spinalized Feline Model." Neural Engineering Center, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH. 2008 July 11.

Mariano TY. "Afferent and Efferent Neural Prosthetic Control of Micturition." Center for Female Pelvic Medicine & Reconstructive Surgery, Glickman Urological Institute, Cleveland Clinic, Cleveland, OH. 2008 May 28.

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