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Email: zachary.nevin@case.edu

 

Zachary  S  Nevin

Entering Class: 2010
PhD Program: Genetics and Genome Sciences
Advisor: Paul Tesar, PhD
Laboratory: BRB 739A

Undergraduate Institution: Stanford University
Hometown: Towson, MD.

Research Interests: I am using patient-derived induced pluripotent stem cells to model genetic myelin disorders such as Pelizaeus-Merzbacher disease.

About me: My primary medical interests are pediatrics and genetics. My research interests broadly include modeling rare diseases with patient-derived stem cells (hiPSCs), identifying and modeling undiagnosed neurogenetic diseases, and gene editing.

Comment about the MSTP program:

Featured Publication:

Nevin et al., Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes, The American Journal of Human Genetics (2017), http://dx.doi.org/10.1016/j.ajhg.2017.03.005

Additional Publications:

Najm FJ, Madhavan M, Zaremba A, Shick E, Karl RT, Factor DC, Miller TE, Nevin ZS, Kantor C, Sargent A, Quick KL, Schlatzer DM, Tang H, Papoian R, Brimacombe KR, Shen M, Boxer MB, Jadhav A, Robinson AP, Podojil JR, Miller SD, Miller RH, Tesar PJ. Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo. Nature. 2015 Jun 11;522(7555):216-20. doi: 10.1038/nature14335. Epub 2015 Apr 20. PubMed PMID: 25896324; PubMed Central PMCID: PMC4528969

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