Briana  C  Prager

Entering Class: 2016
PhD Program:

Undergraduate Institution: Harvard University
Hometown: Stratham, NH.

Research Interests:

About me:

Comment about the MSTP program:

Featured Publication:

Wang X, Huang Z, Wu Q, Prager BC, Mack SC, Yang K, Kim LJY, Gimple RC, Shi Y, Lai S, Xie Q, Miller TE, Hubert CG, Song A, Dong Z, Zhou W, Fang X, Zhu Z, Mahadev V, Bao S, Rich JN. MYC-regulated Mevalonate Metabolism Maintains Brain Tumor Initiating Cells. Cancer Res. 2017 Jul 20. pii: canres.0114.2017. doi: 10.1158/0008-5472.CAN-17-0114. [Epub ahead of print] PubMed PMID: 28729418.

Additional Publications:

Jung J, Kim LJY, Wang X, Wu Q, Sanvoranart T, Hubert CG, Prager BC, Wallace LC, Jin X, Mack SC, Rich JN. Nicotinamide metabolism regulates glioblastoma stem cell maintenance. JCI Insight. 2017 May 18;2(10). pii: 90019. doi: 10.1172/jci.insight.90019. [Epub ahead of print] PubMed PMID: 28515364; PubMed Central PMCID: PMC5436539.

Wang X, Yang K, Xie Q, Wu Q, Mack SC, Shi Y, Kim LJY, Prager BC, Flavahan WA, Liu X, Singer M, Hubert CG, Miller TE, Zhou W, Huang Z, Fang X, Regev A, Suvā ML, Hwang TH, Locasale JW, Bao S, Rich JN. Purine synthesis promotes maintenance of brain tumor initiating cells in glioma. Nat Neurosci. 2017 May;20(5):661-673. doi: 10.1038/nn.4537. Epub 2017 Mar 27. PubMed PMID: 28346452.

Hubert CG, Rivera M, Spangler LC, Wu Q, Mack SC, Prager BC, Couce M, McLendon RE, Sloan AE, Rich JN. A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo. Cancer Res. 2016 Apr 15;76(8):2465-77. doi: 10.1158/0008-5472.CAN-15-2402. Epub 2016 Feb 19. PubMed PMID: 26896279; PubMed Central PMCID: PMC4873351.

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