Entering Class: 2008
PhD Program: Genetics
Advisor: Zhenghe John Wang, PhD
Laboratory: WRB 3204
Undergraduate Institution: University of Rochester
Hometown: Amherst, NY.
Research Interests: My research revolves around the role that paxillin, a target of the tumor suppressor PTPRT, plays in cancer progression.
About me: I'm a Buffalo native that needs medical/graduate school to keep my life balanced because I follow the Bills, Sabres and Chelsea FC. I jog, read (usually Stephen King or historical non-fiction about the Cold War) and take care of my cat Sabretooth.
Comment about the MSTP program: The Case MSTP is very well run from top to bottom. The administration keeps me posted on important deadlines, reminds me of organized activities and feeds me with all the free candy I could ever desire. The program is well-integrated, as I easily completed many PhD requirements during my first two years of medical school and made a seamless transition from medical school to graduate school. Finally, the students in the years above me were very willing to help and provide advice for the years ahead.
Feng X*, Scott A*, Wang Y, Wang L, Zhao Y, Doerner S, Satake M, Croniger CM, Wang Z. PTPRT regulates high-fat diet-induced obesity and insulin resistance. PLOS ONE. 2014 Jun 20;9(6):e100783. doi: 10.1371/journal.pone.0100783. eCollection 2014. PMCID: PMC4065109.
Lim SJ, Scott A, Xiong XP, Vahidpour S, Karijolich J, Guo D, Pei S, Yu YT, Zhou R, Li WX. Requirement for CRIF1 in RNA interference and Dicer-2 stability. RNA Biol. 2014. 11(9):1171-9.
Scott A, Song J, Ewing R, Wang Z. Regulation of protein stability of DNA methyltransferase 1 by post-translational modifications. Acta Biochim Biophys Sin (Shanghai). 2014 Mar;46(3):199-203. doi: 10.1093/abbs/gmt146. Epub 2014 Jan 3. PMCID: PMC3932833
Scott A, Wang Z. Tumour suppressor function of protein tyrosine phosphatase
receptor-T. Biosci Rep. 2011. 31(5):303-7. Review. PMCID: PMC3116232.
Scott A, Wang Z. “Colon cancer” in Systems Biology of Cancer, ed. Sam Thiagalingam. New York: Cambridge University Press. In press.
Yan SJ, Zartman JJ, Zhang M, Scott A, Shvartsman SY, Li WX. "Bistability Coordinates Activation of the EGFR and DPP Pathways in Drosophila Vein Differentiation." Mol Syst Biol. 2009. 5:278.
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