Alexander  Tong

Entering Class: 2011
PhD Program: Pathology/Immunology
Advisor: Alex Huang, MD, PhD

Undergraduate Institution: Rhodes College
Hometown: Dallas, TX.

Research Interests: Cancer Biology/Immunology.

I've completed lab rotations with Alex Huang, Shigemi Matsuyama, and Robert Fairchild.

About me: I'm originally from Dallas, TX and attended Cistercian in Irving for middle and high school. Thereafter, I matriculated at Rhodes College in Memphis, TN to pursue my B.S. in Biochemistry & Molecular Biology, while my permanent home made its way from Texas to Hong Kong to Maryland. As an undergraduate, I was a St. Jude Children's Research Hospital Summer Plus Fellow and subsequently a Pediatric Oncology Education Fellow in the Taosheng Chen Lab, where I completed my Honors Research Thesis and fell in love with bench-to-bedside pediatric oncology research. I'm currently back in 3rd year of medical school after finishing my PhD in the Huang Lab -- check out what we do at!

While not burying myself under medical textbooks or developing temporary thumb paralysis from over-pipetting in the lab, I enjoy playing the violin, supporting my local church, reading sci-fi novels, going Cleveland restaurant hopping, singing karaoke anytime anywhere, watching Korean dramas with impossibly implausible painfully predictable plots, and spending time with my lovely wife.

Musical musings and updates: I've been proud to support Doc Opera as Co-Director of the band and look forward to several more years of successful fundraising for our free clinic. I'm also a volunteer violin teacher at the Joyful Noise Neighborhood Music School, which gives free lessons to children who cannot otherwise afford them.

Comment about the MSTP program: At Case, I've met highly motivated yet down-to-earth MSTP students, with whom I am honored to share the next several years and beyond. I've also come to appreciate how incredibly friendly and helpful the MSTP admins are, particularly when I have questions about class registration, taxes, grant requirements, etc. To top things off, Case has a diverse array of top-notch research mentors to choose from, as well as MSTP Co-Directors who make themselves available to us and actively guide our training. Come visit and see for yourself!

Featured Publication:

Tong AA*, Hashem H*, Eid S, Allen F, Kingsley D, Huang AY. Adoptive natural killer cell therapy is effective in reducing pulmonary metastasis of Ewing sacoma. Oncoimmunology. 2017 Mar 16;6(4):e1303586. doi: 10.1080/2162402X.2017.1303586. eCollection 2017. PubMed PMID: 28507811; PubMed Central PMCID: PMC5414867. *co-first author

Additional Publications:

Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Huang AY, Brennan TV, Bishop DK, Ludewig B, Siebel CW, Radtke F, Luther SA, Maillard I. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. J Clin Invest. 2017 Apr 3;127(4):1574-1588. doi: 10.1172/JCI89535. Epub 2017 Mar 20. Pubmed PMID: 28319044. Pubmed Central PMCID: PMC5373885.

Metheny L 3rd, Eid S, Lingas K, Reese J, Meyerson H, Tong A, de Lima M, Huang AY. Intra-osseous Co-transplantation of CD34-selected Umbilical Cord Blood and Mesenchymal Stromal Cells. Hematol Med Oncol. 2016 1(1):25-29. Epub 2016 Oct 20. doi: 10.15761/HMO.1000105. PubMed PMID: 27882356; PubMed Central PMCID: PMC5117423.

Allen F*, Tong AA*, Huang AY. Unique Transcompartmental Bridge: Antigen-Presenting Cells Sampling across Endothelial and Mucosal Barriers. Front Immunol. 2016 Jun 10;7:231. doi: 10.3389/fimmu.2016.00231. eCollection 2016. Review. PubMed PMID: 27375624; PubMed Central PMCID: PMC4901051. *co-first author

Pondugula SR, Tong AA, Wu J, Cui J, Chen T. Protein phosphatase 2Cβl regulates human pregnane X receptor-mediated CYP3A4 gene expression in HepG2 liver carcinoma cells. Drug Metab Dispos 38: 1411-1416, 2010.

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