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PhD Thesis Topics

Just so you can get a taste of what kinds of research MSTP students might do, this page lists the students that have graduated since 2010, the year they graduated, and the title of their thesis. This list will allow you to see the wide scope of work that is done by students in the MSTP.

  • Ryan Fecteau (2017)
    Pathology/Cancer
    Genome-wide Approaches for Identifying Novel Genetic and Epigenetic Events in Gastrointestinal Cancer
  • Malcolm Hoshi (2017)
    Physiology & Biophysics
    Unveiling Mechanisms Involved in Non-Traditional Cases of Inherited Cardiac Channelopathies
  • Michael Katsnelson (2017)
    Pathology/Immunology
    Cation Channels as Regulators and Effectors of NLRP3 Inflammasome Signaling and IL-1 beta secretion
  • Michael Krause (2017)
    NIH GPP
    Investigation of Genetic Determinants of Drug Response in a Plasmodium falciparum Genetic Cross Using a High-Throughput Screening Method
  • Andrew Lavik (2017)
    Pathology/Cancer
    The Role of Inositol 1,4,5-Trisphosphate Receptor-Interacting Proteins in Regulating Inositol 1,4,5-Trisphosphate Receptor-Dependent Calcium Signals and Cell Survival
  • Bradley Martin (2017)
    Pathology/Immunology
    Cell-type specific role of inflammasome adaptor ASC in the immune response
  • Michelle Nassal (2017)
    Physiology & Biophysics
    Identifying novel therapeutic targets for reentrant arrhythmias
  • Edward Richardson (2017)
    Pathology/Immunology
    Regulation of macrophages by Mycobacterium tuberculosis and the ERK MAP kinase signaling pathway
  • Joseph Vithayathil (2017)
    Neurosciences
    Developmental and post-natal roles for ERK1/2 signaling in the hippocampus
  • Marisa Winkler (2017)
    Molecular Biology & Microbiology
    Fitness and Substrate Specificity among Serine ß-lactamases: a Study of KPC, SHV, and the AmpC of Pseudomonas aeruginosa
  • Charlotte Chung (2016)
    Pharmacology
    Molecular Definition of the Loss of Intestinal Barrier Function in HIV Infection
  • Teresa Evans (2016)
    Neurosciences
    In vivo Observations of Resident Microglia and Blood Derived Macrophages in the Brain and Spinal Cord
  • Candida Goodnough (2016)
    Physiology & Biophysics
    Early Detection of Physiologic and Functional Changes of Common Structural Protein Mutations Underlying Human Diseases by MRI
  • Emily Hamburg-Shields (2016)
    Biology
    Roles of beta-catenin in dermal fibrosis
  • James Liao (2016)
    Biomedical Engineering
    Evaluating Multi-Modal Brain-Computer Interfaces for Controlling Arm Movements Using a Simulator of Human Reaching
  • Emily Nizialek (2016)
    Genetics & Genome Sciences
    KLLN as Tumor Suppressor in Cowden Syndrome and Sporadic Breast Cancers
  • Anthony Scott (2016)
    Genetics & Genome Sciences
    Role of PTPRT in obesity and its substrate paxillin tyrosine-88 in colorectal cancer
  • Charles Su (2016)
    Pathology/Immunology
    Endogenous Memory CD8 T Cells in Cardiac Transplantation
  • Ling Wu (2016)
    Pathology/Immunology
    A Hyper Th17 Response Connects the Psoriasis-Associated ACT1 Variant to Skin Inflammation
  • Kenneth Yan (2016)
    Cell Biology
    Regulation of the Glioma Cancer Stem Cell Hierarchy by Gremlin1
  • Lawrence Goodnough (2015)
    Pathology
    The Role of Wnts in Craniofacial Development
  • Thomas Ladas (2015)
    Biomedical Engineering
    An Optogenetic Approach to Induce Seizure Suppression
  • Sungho Lee (2015)
    Neurosciences
    The Role of CX3CR1 Signaling in Alzheimer’s Disease
  • Debarshi Mustafi (2015)
    Pharmacology
    Genetic Signatures of the Retina in Health and Disease
  • Kendrick Shaw (2015)
    Biology
    Dynamical Architectures for Controlling Feeding in Aplysia californica
  • Kumar Sukhdeo (2015)
    Pathology
    Defining Immunophenotypic Signatures of Stem Cells
  • Lachelle Weeks (2015)
    Pathology/Cancer
    Elucidating a role for uracil DNA glycosylase (UDG) mediated DNA base excision repair in the cellular sensitivity to the antifolate, pemetrexed
  • Brent Cameron (2014)
    Neurosciences
    The Role of Il-1 Receptor-Associated Kinase 4 in Microglial Activation in Alzheimer’s Disease
  • Robert Hyde (2014)
    Neurosciences
    Mnemonic representations of transient stimuli and temporal sequences in the rodent hippocampus in vitro
  • Robert Koeth (2014)
    Pathology
    Dietary Trimethylamines, the Gut Microbiota, and Atherosclerosis
  • Sixto Leal (2014)
    Pathology/Immunology
    Fungal Keratitis: Immune Recognition, Neutrophil-Hyphae Interactions, and Fungal Anti-Oxidative Defenses
  • Paul Lin (2014)
    Biomedical Engineering
    Engineered tracking and delivery of mesenchymal stem cells (MSCs)
  • Sreenath Narayan (2014)
    Biomedical Engineering
    MRI-based Hepatic Fat Content Measurements at 7T
  • Serendipity Rinonos (2014)
    Cell Biology
    Overt and Latent Pathways of Polarity Specification in Zygotes: The Haploid-to-Diploid Transition
  • Christopher Ryder (2014)
    Pharmacology
    The Effects of Acidosis on Survival Pathways in Lymphoid Malignancies
  • Sheela Toprani (2014)
    Physiology & Biophysics
    Mechanisms of Seizure Reduction by Low Frequency Electrical Stimulation
  • Gregory Brown (2013)
    Cell Biology
    Inflammatory Signaling Without a Nucleus: Kinase Cascades Stimulate platelet Shedding of Proinflammatory IL-1{beta}-Rich Microparticles
  • Thomas Foutz (2013)
    Biomedical Engineering
    Energy Efficient Neural Stimulation
  • Jason Molitoris (2013)
    Pathology/Cancer
    Mechanistic Insights into Glucocorticoid-induced Apoptosis and Autophagy in Lymphoid Malignancies
  • Vishal Patel (2013)
    Genetics & Genome Sciences
    Molecular Subsystems in Colon Cancer: Network Approaches to Dissecting Driver Gene Biology
  • Daimon Simmons (2013)
    Pathology/Immunology
    Effects of Toll-Like Receptors and Type I Interferon on Dendritic Cell Maturation and Activation of T Cells
  • Vinod Singaram (2013)
    Genetics & Genome Sciences
    The Role of Neuronal Leak Channels in Anesthesia
  • Kevin Steiner (2013)
    Pathology/Immunology
    Prenatal Priming to Malaria Antigens Increases Susceptibility to HIV Infection
  • Bridgette Christopher (2012)
    Physiology & Biophysics
    Myocardial Insulin Resistance Induced by High Fat Feeding in Heart Failure Is Associated with Preserved Contractile Function
  • Sarah Drawz (2012)
    Pathology
    Inhibition of Class A and Class C beta-Lactamases: Challenges and Promise
  • Obinna Ndubuizu (2012)
    Physiology & Biophysics
    Oxygen Sensing, Hypoxia Inducible Factor 1 (HIF-1) Expression, and Hypoxic-Induced Angiogenesis in the Aged Rat Brain
  • Vicki Nelson (2012)
    Genetics & Genome Sciences
    Transgenerational Genetic Effects in Mouse Models of Complex Traits
  • Eugene Oh (2012)
    Neurosciences
    Control of 5-HT1A Receptor Signaling by Chimeric Light-Activated G Protein-Coupled Receptors
  • Ravi Patel (2012)
    Biomedical Engineering
    Development of a Novel Combined Experimental and Modeling Approach to Characterize In Situ Forming Implants for Intratumoral Drug Delivery
  • Vipul Sheth (2012)
    Biomedical Engineering (PETP)
    A CEST MRI Method to Measure pH
  • Nikolai Sopko (2012)
    Cell Biology
    The Effects of Age on Stem Cell Mediated Repair of the Heart in Pressure Overload
  • Arundhati Undurti (2012)
    Cell Biology
    Role of Myeloperoxidase Mediated Oxidative Modification and Apolipoprotein Composition in High Density Lipoprotein Function
  • David Yao (2012)
    Pathology/Immunology
    Role of O-fucose Molecules in Notch Signaling and Hematopoiesis
  • Atheir Abbas (2011)
    Biochemistry
    PSD-95 Regulates Serotonin Receptor Function in vivo
  • Jeffrey Beamish (2011)
    Biomedical Engineering (PETP)
    Engineering Poly(Ethylene Glycol) Hydrogel Scaffolds to Modulate Smooth Muscle Cell Phenotype
  • Andrew Blum (2011)
    Physiology & Biophysics
    Rho Family GTPases as Modulators of Constitutive and Receptor-Stimulated ATP Release in Human Astrocytes
  • Adam Burgoyne (2011)
    Molecular & Microbiology
    Protein Tyrosine Phosphatase Mu Regulates Glioblastoma Cell Migration and Dispersal
  • Jamal Derakhshan (2011)
    Biomedical Engineering (PETP)
    Innovations Involving Balanced Steady State Free Precession MRI
  • Michael Drage (2011)
    Pathology/Immunology
    A Novel Mechanism of TLR2 Activation by Mycobacterium tuberculosis Lipoprotein LprG
  • Charlene Kan (2011)
    Genetics & Genome Sciences
    Cellular Changes and Effects of Cytokines In the Transformation of Human Mammary Epithelial Cells
  • Laura Kopplin (2011)
    Genetics & Genome Sciences
    Identifying Genetic Risk Factors for Age-Related Macular Degeneration
  • Phillip Larimer (2011)
    Neurosciences
    The role of dentate hilus intrinsic circuits in persistent activity
  • Timothy Mariano (2011)
    Biomedical Engineering
    Electrical Stimulation of Afferent Neural Pathways for Suppression of Urethral Reflexes
  • Molly Miller (2011)
    Pharmacology
    Comparative characterization of the major human glutaredoxin isozymes and the impact of diminished Grx1 on oxidant-induced apoptosis in cardiomyocytes
  • Marjorie Montanez-Wiscovich (2011)
    Pharmacology
    Evaluating the Role of LMO4 in ErbB2-induced Breast Cancer
  • Joshua Rosenblum (2011)
    Pathology/Immunology
    Novel Roles for Chemokines in Acute Cardiac Allograft Rejection
  • David Chang (2010)
    Biomedical Engineering
    Lymphocyte and Macrophage Interactions in the Response to Biomaterial surfaces
  • Elizabeth Chiang (2010)
    Neurosciences
    Investigation of the electrophysiological properties of the major cell types in the rat olfactory tubercle
  • Justin Hartupee (2010)
    Pathology/Immunology
    Regulation of mRNA Stability in Chemokine Gene Expression
  • Matthew Kalp (2010)
    Biochemistry
    Application of Raman Crystallography to Biological Systems
  • Lenette Lu (2010)
    Molecular Virology
    dsRNA Signaling in Innate Immunity and Viral Inhibition
  • Shibani Mukerji (2010)
    Neurosciences
    Activin A Reduces Brain Injury after Stroke
  • Nicole Pecora (2010)
    Pathology
    TLR2-dependent modulation of antigen presenting cell functions by mycobacterial lipoproteins
  • Austin Schenk (2010)
    Pathology/Immunology
    CD 8 Memory T Cell Function During the 72 Hours Immediately Following Cardiac Allograft Reperfusion
  • Michael Sobieraj (2010)
    Mechanical & Aerospace Engineering
    Static and Cyclic Behavior of UHMWPE and PEEK Orthopaedic Polymers in the Presence of Mild Stress Risers
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