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PhD Thesis Topics

Just so you can get a taste of what kinds of research MSTP students might do, this page lists the students that have graduated since 2001, the year they completed their PhD, and the title of their thesis. This list will allow you to see the wide scope of work that is done by students in the MSTP.

  • Candida Goodnough (2015)
    Biomedical Engineering
    Early Detection of Physiologic and Functional Changes of Common Structural Protein Mutations Underlying Human Diseases by MRI
  • Charlotte Chung (2014)
    Medicine (Gastroenterology and Hepatology)
    Molecular Definition of the Loss of Intestinal Barrier Function in HIV Infection
  • Teresa Evans (2014)
    Neurosciences
    In vivo Observations of Resident Microglia and Blood Derived Macrophages in the Brain and Spinal Cord
  • Emily Hamburg-Shields (2014)
    Biology
    Roles of beta-catenin in dermal fibrosis
  • James Liao (2014)
    Biomedical Engineering
    Evaluating Multi-Modal Brain-Computer Interfaces for Controlling Arm Movements Using a Simulator of Human Reaching
  • Emily Nizialek (2014)
    CCF Cancer Genomic Medicine
    KLLN as Tumor Suppressor in Cowden Syndrome and Sporadic Breast Cancers
  • Vijay Pandyarajan (2014)
    Biochemistry
    Structure-function relationships at a hormone-receptor interface: insulin residues B24 and B26
  • Anthony Scott (2014)
    Genetics & Genome Sciences
    Role of PTPRT in obesity and its substrate paxillin tyrosine-88 in colorectal cancer
  • Charles Su (2014)
    CCF Immunology
    Endogenous Memory CD8 T Cells in Cardiac Transplantation
  • Sheela Toprani (2014)
    Physiology & Biophysics
    Mechanisms of seizure reduction by low frequency electrical stimulation
  • Ling Wu (2014)
    CCF Immunology
    A Hyper Th17 Response Connects the Psoriasis-Associated ACT1 Variant to Skin Inflammation
  • Kenneth Yan (2014)
    CCF Stem Cell Biology & Regenerative Med
    Regulation of the Glioma Cancer Stem Cell Hierarchy by Gremlin1
  • Henry Goodnough (2013)
    Pathology
    The role of Wnts in craniofacial development
  • Robert Koeth (2013)
    Pathology
    Dietary trimethylamines, the gut microbiota, and atherosclerosis
  • Thomas Ladas (2013)
    Biomedical Engineering
    An Optogenetic Approach to Induce Seizure Suppression
  • Sungho Lee (2013)
    Neurosciences
    The Role of CX3CR1 Signaling in Alzheimer’s Disease
  • Debarshi Mustafi (2013)
    Pharmcology
    Genetic Signatures of the Retina in Health and Disease
  • Kendrick Shaw (2013)
    Biology
    Dynamical Architectures for Controlling Feeding in Aplysia californica
  • Kumar Sukhdeo (2013)
    Pathology
    Defining Immunophenotypic Signatures of Stem Cells
  • Lachelle Weeks (2013)
    Pathology/Cancer
    Elucidating a role for uracil DNA glycosylase (UDG) mediated DNA base excision repair in the cellular sensitivity to the antifolate, pemetrexed
  • Brent Cameron (2012)
    Neurosciences
    The role of Il-1 receptor-associated kinase 4 in microglial activation in Alzheimer’s Disease
  • Robert Hyde (2012)
    Neurosciences
    Mnemonic representations of transient stimuli and temporal sequences in the rodent hippocampus in vitro
  • Sixto Leal (2012)
    Pathology/Immunology
    Fungal keratitis: immune recognition, neutrophil-hyphae interactions, and fungal anti-oxidative defenses
  • Paul Lin (2012)
    Biomedical Engineering
    Engineered tracking and delivery of mesenchymal stem cells (MSCs)
  • Sreenath Narayan (2012)
    Biomedical Engineering
    MRI-based hepatic fat content measurements at 7T
  • Serendipity Rinonos (2012)
    Cell Biology
    Overt and latent pathways of polarity specification in zygotes: the haploid-to-diploid transition
  • Christopher Ryder (2012)
    Pharmacology
    The effects of acidosis on survival pathways in lymphoid malignancies
  • G. Tom Brown (2011)
    Cell Biology
    Inflammatory signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1{beta}-rich microparticles
  • Thomas Foutz (2011)
    Biomedical Engineering
    Energy efficient neural stimulation
  • Jason Molitoris (2011)
    Pathology/Cancer
    Mechanistic insights into glucocorticoid-induced apoptosis and autophagy in lymphoid malignancies
  • Daimon Simmons (2011)
    Pathology/Immunology
    Effects of toll-like receptors and type I interferon on dendritic cell maturation and activation of T cells
  • Vinod Singaram (2011)
    Genetics
    The role of neuronal leak channels in anesthesia
  • Kevin Steiner (2011)
    Pathology/Immunology
    Prenatal priming to malaria antigens increases susceptibility to HIV infection
  • Bridgette Christopher (2010)
    Physiology & Biophysics
    Myocardial insulin resistance induced by high fat feeding in heart failure is associated with preserved contractile function
  • Sarah Drawz (2010)
    Pathology
    Inhibition of class A and class C beta-lactamases: challenges and promise
  • Obinna Ndubuizu (2010)
    Physiology & Biophysics
    Oxygen sensing, hypoxia inducible factor 1 (HIF-1) expression, and hypoxic-induced angiogenesis in the aged rat brain
  • Vicki Nelson (2010)
    Genetics
    Transgenerational genetic effects in mouse models of complex traits
  • Eugene Oh (2010)
    Neurosciences
    Control of 5-HT1A receptor signaling by chimeric light-activated G protein-coupled receptors
  • Ravi Patel (2010)
    Biomedical Engineering
    Development of a novel combined experimental and modeling approach to characterize in situ forming implants for intratumoral drug delivery
  • Vipul Sheth (2010)
    Biomedical Engineering (PETP)
    A CEST MRI method to measure pH
  • Nikolai Sopko (2010)
    Cell Biology
    The effects of age on stem cell mediated repair of the heart in pressure overload
  • Arundhati Undurti (2010)
    Cell Biology
    Role of myeloperoxidase mediated oxidative modification and apolipoprotein composition in high density lipoprotein function
  • David Yao (2010)
    Pathology/Immunology
    Role of O-fucose molecules in notch signaling and sematopoiesis
  • Atheir Abbas (2009)
    Biochemistry
    PSD-95 Regulates Serotonin Receptor Function in vivo
  • Jeffrey Beamish (2009)
    Biomedical Engineering (PETP)
    Engineering Poly(Ethylene Glycol) Hydrogel Scaffolds to Modulate Smooth Muscle Cell Phenotype
  • Andrew Blum (2009)
    Physiology & Biophysics
    Rho Family GTPases as Modulators of Constitutive and Receptor-Stimulated ATP Release in Human Astrocytes
  • Adam Burgoyne (2009)
    Molecular & Microbiology
    Protein Tyrosine Phosphatase Mu Regulates Glioblastoma Cell Migration and Dispersal
  • Jamal Derakhshan (2009)
    Biomedical Engineering (PETP)
    Innovations Involving Balanced Steady State Free Precession MRI
  • Michael Drage (2009)
    Pathology/Immunology
    A Novel Mechanism of TLR2 Activation by Mycobacterium tuberculosis Lipoprotein LprG
  • Matthew Kalp (2009)
    Biochemistry
    Application of Raman Crystallography to Biological Systems
  • Charlene Kan (2009)
    Genetics
    Cellular Changes and Effects of Cytokines In the Transformation of Human Mammary Epithelial Cells
  • Laura Kopplin (2009)
    Genetics
    Identifying Genetic Risk Factors for Age-Related Macular Degeneration
  • Phillip Larimer (2009)
    Neurosciences
    The role of dentate hilus intrinsic circuits in persistent activity
  • Timothy Mariano (2009)
    Biomedical Engineering
    Electrical Stimulation of Afferent Neural Pathways for Suppression of Urethral Reflexes
  • Molly Miller (2009)
    Pharmacology
    Comparative characterization of the major human glutaredoxin isozymes and the impact of diminished Grx1 on oxidant-induced apoptosis in cardiomyocytes
  • Marjorie Montanez-Wiscovich (2009)
    Pharmacology
    Evaluating the Role of LMO4 in ErbB2-induced Breast Cancer
  • Shibani Mukerji (2009)
    Neurosciences
    Activin A Reduces Brain Injury after Stroke
  • Joshua Rosenblum (2009)
    Pathology/Immunology
    Novel Roles for Chemokines in Acute Cardiac Allograft Rejection
  • Michael Sobieraj (2009)
    Mechanical & Aerospace Engineering
    Static and Cyclic Behavior of UHMWPE and PEEK Orthopaedic Polymers in the Presence of Mild Stress Risers
  • Candice Bookwalter (2008)
    Biomedical Engineering
    Continuous Sampling in Magnetic Resonance Imaging
  • David Chang (2008)
    Biomedical Engineering
    Lymphocyte and Macrophage Interactions in the Response to Biomaterial surfaces
  • Elizabeth Chiang (2008)
    Neurosciences
    Investigation of the electrophysiological properties of the major cell types in the rat olfactory tubercle
  • Justin Hartupee (2008)
    Pathology/Immunology
    Regulation of mRNA Stability in Chemokine Gene Expression
  • Lenette Lu (2008)
    Molecular Virology
    dsRNA Signaling in Innate Immunity and Viral Inhibition
  • Stephen Ostrowski (2008)
    Neurosciences
    Pleiotropic Mechanisms of Statin Action in Alzheimer’s Disease
  • Nicole Pecora (2008)
    Pathology
    TLR2-dependent modulation of antigen presenting cell functions by mycobacterial lipoproteins
  • Analiz Rodriguez (2008)
    Pathology
    in vivo Macrophage/Lymphocyte Reactivity to Biomaterials
  • Catherine Rottkamp (2008)
    Neurosciences
    The Role of Hox Cofactors in Vertebrate Spinal Cord Development
  • Austin Schenk (2008)
    Pathology/Immunology
    CD 8 Memory T Cell Function During the 72 Hours Immediately Following Cardiac Allograft Reperfusion
  • Mursalin Anis (2007)
    Pathology
    Modulation of naive CD4+ T cell activation and lung dendritic cell function in the lungs during pulmonary mycobacterial infection
  • Ahmad (Sami) Chaouki (2007)
    Genetics: Mol, Dev & Human
    SPF45, a protein with functions in both splicing and DNA repair
  • Christopher Elco (2007)
    Molecular Virology
    Regulation of dsRNA-Induced Transcription by NFkappaB and IRF-3 through TLR3 and RIG-I
  • Michele Etling (2007)
    Pathology
    The Aging Mucosal Immune System in the Interleukin-10-Deficient Mouse
  • Molly Fuller (2007)
    Neurosciences
    The Role of Bone Morphogenetic Proteins in Reactive Gliosis after Demyelinating Spinal Cord Lesions
  • Christy Gray (2007)
    Neurosciences
    Extracellular and Intracellular Regulation of Axon Outgrowth in Hippocampus: A role for RPTP-beta/zeta, ezrin, and hnRNP-U
  • Aryavarta Kumar (2007)
    Biomedical Engineering (PETP)
    Molecular Engineering of a Self-Assembling Nucleobase Coating with Nano-Scale Control
  • Coby Larsen (2007)
    Biomedical Engineering (PETP)
    Endothelial Cell Growth, Shear Stability, and Function on Biomimetic Peptide Fluorosurfactant Polymers
  • Michael Lobritz (2007)
    Molecular & Microbiology
    Variations in the V3 Crown of HIV-1 Envelope Impact Affinity for CCR5 and Affect Entry and Replicative Fitness
  • Svjetlana Miocinovic (2007)
    Biomedical Engineering
    Theoretical and Experimental Predictions of Neural Elements Activated by Deep Brain Stimulation
  • Jonathan Mosley (2007)
    Pharmacology
    Elucidating the Molecular Signaling Pathways in Normal and Malignant Mammary Glands Using Transgenic Mouse Models
  • Davis Ryman (2007)
    Genetics
    Genetic and Environmental Modifiers of Amyloid-Beta Metabolism and Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease
  • Mark Samols (2007)
    Molecular Virology
    Identification and Functional Analysis of MicroRNAs Encoded by Kaposi's Sarcoma-Associated Herpesvirus
  • David Shultz (2007)
    Pathology
    The role of IKKbeta in IFN-gamma signaling
  • Jodi Thomson (2007)
    Pharmacology
    Overcoming Inhibitor Resistance in the SHV Beta-Lactamase
  • Brent Weinberg (2007)
    Biomedical Engineering
    Intratumoral Chemotherapy for Liver Cancer Using Biodegradable Polymer Implants
  • Ramani Balu (2006)
    Neurosciences
    Systems neurobiology; theoretical and electrophysiological analysis of neural circuits involved in sensory perception
  • Tehnaz Boyle (2006)
    Pharmacology
    Transcriptional Regulation of Steroidogenesis by FSH Requires ß-catenin
  • Lindsay Burrage (2006)
    Genetics: Mol, Dev & Human
    Genetic Resistance to Diet-Induced Obesity in Mice
  • Michael Davis (2006)
    Pharmacology
    The role of the inositol triphosphate receptor in glucocorticoid-induced apoptosis.
  • Roger Lin (2006)
    Biomedical Engineering
    Optical Coherence Tomography
  • Dolly Ann Padovani-Claudio (2006)
    Neurosciences
    Functional analyses of the chemokine receptor cxcr2 in the normal and demyelinated adult central nervous system
  • Mark Ruszczycky (2006)
    Biochemistry
    V/K Isotope Effects on Enzyme Catalyzed Nucleophilic Attack: The Case of Serine O-Acetyltransferase
  • James Bayrer (2005)
    Pharmacology
    Characterization of the Drosophila Transcription Factor Doublesex, and its Role in Sex Determination and Development.
  • Bryan Carroll (2005)
    Genetics: Mol, Dev & Human
    Characterization of Stomatin Suppressors ssu-1 and ssu-2.
  • Andrew Cordle (2005)
    Neurosciences
    "Investigation of the molecular mechanisms underlying the inflammatory component of Alzheimer's disease."
  • David Rhee (2005)
    Genetics: Mol, Dev & Human
    Investigating the biology of a protein whose genetic deficiency results in a rare genetic disease that perturbs normal joint function.
  • Brenda Rivera-Reyes (2005)
    Pathology
    Regulation of T cell signaling and activation
  • Lewis Rosenberg (2005)
    Genetics: Mol, Dev & Human
    The function of the anterior pituitary (AP) in a murine model of CF.
  • Amelia Sutton (2005)
    Pharmacology
    Characterizing Novel Vitamin D-Regulated Genes in Osteoblasts: Implications for Skeletal Development and Maintenance
  • Tarek El-Sawy (2004)
    Pathology
    The Induction and Role of Neutrophil Chemokines Following Solid Organ Transplantation
  • Daniel Jane-Wit (2004)
    Pathology
    Divergent Gender-Specific Immune Responses to a Cardiac Self-Antigen”
  • Michelle Kahlenberg (2004)
    Pathology
    Investigating the role of the P2X7 receptor in MAP Kinase Signaling
  • Daniel Leventhal (2004)
    Biomedical Engineering
    Nerve reshaping for improved electrode selectivity
  • Aneta Reszko (2004)
    Biochemistry
    Paradoxical regulation of Serotonin 5-HT2A receptors by Arrestins
  • Darrell Rubin (2004)
    Pathology
    Acute Regulation of Glut1 Function: The Role of Detergent-Resistant Membrane Domains"
  • Aaron Tobian (2004)
    Pathology
    Examining the role of the alternate MHC-I antigen processing pathway with Mycobacterium tuberculosis and heat shock proteins.
  • Philip Alan Verhoef (2004)
    Pharmacology
    Exploring the mechanisms of membrane blebbing and their relationship to Interleukin-1ß secretion in murine macrophages
  • Joshua Friedman (2003)
    Genetics
    TGF-beta receptor deficiency in mice and novel TGF-ß regulated gene with lost expression in colon cancer
  • John Gray (2003)
    Biochemistry
    Paradoxical regulation of Serotonin 5-HT2A receptors by Arrestins
  • Roee Lazebnik (2003)
    Biomedical Engineering
    Magnetic resonance imaging guided radiofrequency thermal ablation therapy
  • Rish Pai (2003)
    Pathology
    Immunology - innate immunity
  • Edmunds Reineks (2003)
    Pharmacology
    Mechanisms of DNA polymerase fidelity revealed by kinetic analysis
  • Andrew Schade (2003)
    Pathology
    Molecular mechanisms of T lymphocyte activation
  • David Wald (2003)
    Pathology
    Signaling pathways and biological functions for members of the Toll/IL-1 Receptor superfamily
  • Zongqi Xia (2003)
    Neurosciences
    Regulation of 5-HT2A serotonin receptor trafficking and signaling in cortical pyramidal neurons
  • Michael Altose (2002)
    Biochemistry
    Applications of raman spectroscopy and microscopy and to the investigation of biological systems
  • Jeffrey Bailey (2002)
    Genetics
    Genome-wide detection and analysis of segmental duplications
  • Kalonji Collins (2002)
    Molecular Virology
    The effects of tuberculosis on HIV-1 heterogeneity, quasispecies distribution, and implications on viral fitness
  • Anne Deucher (2002)
    Biochemistry
    Regulation of epidermal keratinocyte growth and differentiation by calcium and retinoic acid
  • Alexander Garber (2002)
    Molecular and Microbiology
    Functional analysis of the latency associated nuclear antigen of Kaposi's sarcoma-associated nuclear antigen
  • Robin Jump (2002)
    Pathology
    T cells maintain natural tolerance in the intestinal mucosa through antigen education in Peyer's patches
  • Gabe Owens (2002)
    Pharmacology
    Elucidating the molecular pathways governing hormone-induced granulosa cell tumorigenesis
  • Nicholas Potter (2002)
    Pathology
    Alternate MHC-1 processing pathways
  • Jullia Rosdahl (2002)
    Molecular and Microbiology
    Signaling in the growth cone: PTPmu and its downstream pathways
  • Dana Schwarz (2002)
    Genetics
    Genetic studies of mouse sorting Nexins 1 and 2
  • Brian Lestini (2001)
    Biomedical Engineering
    Use of liposome vesicles for cellular targeting of drugs
  • Shannon Morris (2001)
    Molecular Virology
    Reverse transcription by avian retroviruses
  •